FlorRhein-10
Antibiotic
FORMULA:
Every ml of product contains:
Florfenicol............................... 100 mg
Excipients q.s............................... 1 ml
DESCRIPTION:
FlorRhein-10 is a broad spectrum antibiotic of excellent intestinal absorption, broad safety margins, great resistance to bacterial inactivation and fast tissue elimination.
FlorRhein-10 has showed a broader spectrum than chloramphenicol and even its other analogous: tiamphenicol. It also shows a good activity against some chloramphenicol resistant bacterias. As it is considered that the chloramphenicol p-nitro group causes aplastic anemia in the human, some radicals have been replaced in the florfenicol structure, for example, the third carbon hydroxyl group has been replaced with a fluorine atom, keeping the same chloramphenicol shape in space and the same as in the thiamphenicol, the p-nitro group is replaced by a sulphur radical. Chloramphenicol and thiamphenicol can be inactivated by Enterobacteriae gender by acetylation of the hydroxyl group in 1 and 3 carbon atoms, in the propanediol chain which cannot happen with florfenicol due to its fluorine union making it stronger against pathogenic microorganisms in comparison to its two analogous.
INDICATIONS:
Healing treatment for enteric and respiratory infections caused by E.coli and other bacteria sensitive to florfenicol causing: colibacillary enteritis, respiratory colibacillosis, colisepticemia, complications with E. coli infectious diseases (coryza, c.r.d.)
SUSCEPTIBLE ORGANISMS:
Gram negative: Pasteurella haemolytica, Pasteurella multocida, Haemophilus sommus, Haemophilus influenzae, Escherichia coli, Salmonella spp, Moraxella spp, Klebsiella spp, Enterococcus spp, Shigella spp, Treponema hyodysenteriae, Bacteroides spp, Bordetella bronchiseptica, Proteus spp, Neisseria spp.
Gram positive: Corynebacterim pyogenes, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, Streptococcus zooepidermicus, Streptococcus aureus.
For the treatment of poultry: broilers, breeders, replacement pullets.
DOSAGE AND USAGE:
Dissolve by oral means in drinking water to the rate of 20 mg/kg. b. w. during 3 to 5 days.
WARNINGS:
Keep out of the reach of children.
Avoid contact with product. If accidental exposure occurs, wash with tap water and soap.
Wear suitable outfit when medicine is being administered.
Wash hands and change clothes after administration.
Store in original container at a temperature between 0º and 30º C.
Use Restrictions:
Withdrawal period: 5 days.
Do not use with penicillin jointly.
Do not use in laying hens producing eggs for human consumption.
PRESENTATION:
500 ml and 1 litre containers.
Veterinary use